Presents:

Biomechanical Models of Knee Joint Arthroplasty



Date:
May 16th, 2008
Time: 2:00pm - 3:00pm
Location: Fung Auditorium, Bioengineering Hall, UCSD


DESCRIPTION/ABSTRACT:
Total knee arthroplasty is the surgical procedure of choice for end-stage arthritis. Nearly 300,000 such procedures are performed annually in the US. The need for total knee arthroplasty is expected to rise dramatically as the "baby boomer" population segment ages. The biomechanics of the knee joint is a major factor affecting the function and long-term survival of implanted prosthesis. A "smart" knee implant was developed to measure knee forces in vivo in patients after knee arthroplasty. This implant contains force sensors, a microprocessor, and a telemetry system for wireless monitoring of knee forces. Knee forces after total knee replacement are directly related to the transmission of stresses including contact stresses generated at the bearing surface, stresses at the implant-cement-bone interface and stresses transmitted to underlying bone. These stresses are a major factor in wear and fatigue, aseptic loosening and implant migration, bone remodeling, stress shielding and osteoporosis, all of which determine the life of the implant. This seminar presents the knee forces measured during activities of daily living, recreational activities, and exercise. The effect of these forces on prosthetic materials is discussed. In vivo measured forces can be used to develop more accurate biomechanical models of the knee. Knowledge of in vivo forces can be used to design more effective in vitro knee testing devices that can accurately model knee function and prosthetic wear. Finally, these results can directly enhance prosthetic design.


Guest Speaker:
Darryl D'Lima, M.D., Scripps Clinic
Director, Orthopaedic Research Laboratories
Darryl D'Lima, MD, PhD trained in India as an orthopaedic surgeon and at Scripps Clinic, CA as a fellow in Adult Reconstruction under Clifford W. Colwell Jr, MD. He received his PhD in Bioengineering at UC San Diego, CA. He is currently Director, Orthopaedic Research Laboratories at the Shiley Center for Orthopaedic Research and Education (SCORE) at Scripps Clinic and an Assistant Professor in the Division of Arthritis Research at Scripps Research Institute. Dr. D'Lima's major research interests include biomechanics of the hip and knee joints, and cartilage injury and repair. In 2005 he received the AAOS Kappa Delta award for his work on chondrocyte apoptosis following cartilage injury. He has also received two Knee Society awards and the HAP Paul award from ISTA for research involving the development of the "smart" knee prosthesis.


MORE INFORMATION:
For a complete listing of Bioengineering seminars, please visit http://be-web.ucsd.edu/events/seminars.



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Date:

Friday, May 16, 2008
2:00PM-3:00PM
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Location:

9500 Gilman Drive
La Jolla, CA 92093